Fardy M J, Zakrzewska J M, Patton D W
Department of Oral Surgery, Morriston Hospital, Swansea, U.K.
Acta Neurochir (Wien). 1994;129(3-4):181-4; discussion 185. doi: 10.1007/BF01406500.
Trigeminal neuralgia remains a difficult condition to manage. Surgery aimed at peripheral nerve branches continues to be used extensively by oral and maxillofacial surgeons. The efficacy of 68 peripheral alcohol injections (retrospective study) and 22 peripheral glycerol injections (prospective study) were assessed in comparison with peripheral cryotherapy. The results indicate that the median time for total pain control after the first alcohol block was 13 months. When individual branches were assessed it was 13 months for the infra-orbital nerve and 19 months for the inferior alveolar nerve. These results compare with the published results on cryotherapy. The results for glycerol were disappointing with a mean time of pain relief of 7 months. The results suggest that peripheral alcohol nerve blocks do still have a role to play in the management of trigeminal neuralgia, particularly in the elderly, medically compromised and those unwilling to undergo more extensive surgery. They also provide a means of temporary relief.
三叉神经痛仍然是一种难以治疗的疾病。针对周围神经分支的手术仍被口腔颌面外科医生广泛应用。与周围冷冻疗法相比，评估了68次周围酒精注射（回顾性研究）和22次周围甘油注射（前瞻性研究）的疗效。结果表明，首次酒精阻滞术后完全控制疼痛的中位时间为13个月。当评估单个分支时，眶下神经为13个月，下牙槽神经为19个月。这些结果与已发表的冷冻疗法结果进行了比较。甘油注射的结果令人失望，平均疼痛缓解时间为7个月。结果表明，周围酒精神经阻滞在三叉神经痛的治疗中仍有作用，特别是对于老年人、有医学并发症的患者以及那些不愿接受更广泛手术的患者。它们还提供了一种临时缓解的方法。
