Du G
Baise City People's Hospital, Guang Xi.
Zhonghua Liu Xing Bing Xue Za Zhi. 1994 Oct;15(5):278-81.
ELISA was used to detect anti-HCV antibody in 179 serum samples of patients with various types of liver diseases and 41 serum samples of blood recipients in Baise district of Guang Xi. The results showed that 17.9% of patients with various types of liver diseases and 31.7% of blood recipients were anti-HCV positive. Among patients with liver diseases, the anti-HCV positive rate was 4.3% (1/23) in acute hepatitis (AH), 12.8% (10/78) in chronic hepatitis (CH), 28.6% (12/42) in liver cirrhosis (LC) and 25.0% (9/36) in hepatocellular carcinoma (HCC). As liver diseases became chronic, the anti-HCV positive rate tended to rise. The anti-HCV positive rate in LC was significantly higher than that in AH or CH (P < 0.05). The anti-HCV positive rate in HCC was not significantly different from that in AH or CH (P > 0.05 or 0.1). It was found that the anti-HCV positive rate in HBsAg-negative patients was significantly higher than that in HBsAg-positive patients (P < 0.05). The anti-HCV positive rate in liver diseases was not related to ALT (P > 0.05). In blood recipients, the anti-HCV positive rate was closely related to the number of transfusion and the activity of ALT.
采用酶联免疫吸附试验（ELISA）检测广西百色地区179例各类肝病患者血清样本及41例受血者血清样本中的抗丙型肝炎病毒（HCV）抗体。结果显示，各类肝病患者中17.9%抗-HCV阳性，受血者中31.7%抗-HCV阳性。在肝病患者中，急性肝炎（AH）抗-HCV阳性率为4.3%（1/23），慢性肝炎（CH）为12.8%（10/78），肝硬化（LC）为28.6%（12/42），肝细胞癌（HCC）为25.0%（9/36）。随着肝病转为慢性，抗-HCV阳性率呈上升趋势。LC患者抗-HCV阳性率显著高于AH或CH患者（P<0.05）。HCC患者抗-HCV阳性率与AH或CH患者相比差异无统计学意义（P>0.05或0.1）。发现乙肝表面抗原（HBsAg）阴性患者抗-HCV阳性率显著高于HBsAg阳性患者（P<0.05）。肝病患者抗-HCV阳性率与丙氨酸氨基转移酶（ALT）无关（P>0.05）。在受血者中，抗-HCV阳性率与输血次数及ALT活性密切相关。
