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[碘缺乏所致疾病的预防:神经心理学筛查经验]

[The prevention of disorders due to iodine deficiency: the experience of neuropsychological screening].

作者信息

Ferretti G

机构信息

Istituto di Ricovero e Cura a Carattere Scientifico Stella Maris, Università degli Studi, Pisa.

出版信息

Ann Ist Super Sanita. 1994;30(3):347-51.

PMID:7533488
Abstract

In this research we investigated some neuropsychological parameters in school-age children living in two areas in which mild iodine deficiency has been found in the past. In Study 1 no significant difference was found in cognitive (WISC-R Block Design test), visuo-motor (WISC-R Coding test modified) and fine distal movements tasks. On the other hand in a Simple Reaction Time task children living in iodine deficient area were significantly slower than controls. In Study 2 the same results were obtained in the group of children born before an extensive iodine prophylaxis program, but not in younger children born later. Our data show that exposure to mild iodine deficiency in fetal/neonatal life does not affect general cognitive performance but slows the speed of motor responses, which may be due to an impairment concerning neural transmission mechanisms.

摘要

在本研究中,我们调查了生活在过去曾发现轻度碘缺乏的两个地区的学龄儿童的一些神经心理学参数。在研究1中,认知(韦氏儿童智力量表修订版积木图案测试)、视觉运动(改良的韦氏儿童智力量表译码测试)和精细远端运动任务方面未发现显著差异。另一方面,在简单反应时间任务中,生活在碘缺乏地区的儿童明显比对照组慢。在研究2中,在广泛的碘预防计划实施前出生的儿童组中得到了相同的结果,但在之后出生的年幼儿童中未得到相同结果。我们的数据表明,胎儿/新生儿期暴露于轻度碘缺乏不会影响一般认知能力,但会减慢运动反应速度,这可能是由于神经传递机制受损所致。

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