在古生菌嗜热栖热菌中，一个编码假定膜蛋白的基因与转运蛋白主要易化子超家族同源，该基因位于β-糖苷酶基因的上游。
A gene encoding a putative membrane protein homologous to the major facilitator superfamily of transporters maps upstream of the beta-glycosidase gene in the archaeon Sulfolobus solfataricus.
作者信息
Prisco A, Moracci M, Rossi M, Ciaramella M
机构信息
Institute of Protein Biochemistry and Enzymology, Consiglio Nazionale delle Ricerche, Naples, Italy.
出版信息
J Bacteriol. 1995 Mar;177(6):1614-9. doi: 10.1128/jb.177.6.1614-1619.1995.
Abstract
We have identified a gene encoding a putative membrane protein homologous to the major facilitator superfamily, mapping upstream of the lacS gene in Sulfolobus solfataricus. Permeases from this family mediate secondary transport and are widely distributed among eubacteria and eukaryotes; the finding of an archaeal member suggests that this mechanism of transport evolved before the divergence of the three living domains. We also report a transcriptional mapping of the gene cluster.
摘要
我们已经鉴定出一个编码推定膜蛋白的基因，该蛋白与主要易化子超家族同源，定位于嗜热栖热菌中lacS基因的上游。该家族的通透酶介导次级转运，广泛分布于真细菌和真核生物中；发现古菌成员表明这种转运机制在三个生命域分化之前就已进化。我们还报告了该基因簇的转录图谱。
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