Buisseret P D
Lancet. 1978 Feb 11;1(8059):304-5. doi: 10.1016/s0140-6736(78)90072-7.
Cow's milk allergy was diagnosed in 79 patients, all of whom had signs and symptoms of allergies other than milk intolerance. In addition to difficulties with infant feeding and diarrhoea, clinical features included constipation, vomiting, intestinal colic, growth retardation, and psychological disturbance, as well as eczema and asthma. All were reversible after milk withdrawal, which suggests that the allergic basis of such symptoms may have been underestimated. In most cases, one or both parents were atopic and the child had been bottle-fed from birth. There were no breast-fed children of non-atopic parents in this series.
79名患者被诊断出对牛奶过敏,他们所有人除了不耐受牛奶外,还有其他过敏的体征和症状。除了婴儿喂养困难和腹泻外,临床特征还包括便秘、呕吐、肠痉挛、生长发育迟缓、心理障碍,以及湿疹和哮喘。停止食用牛奶后,所有症状都可逆转,这表明此类症状的过敏基础可能一直被低估。在大多数情况下,父母一方或双方都有特应性,且孩子从出生就一直用奶瓶喂养。该系列中没有非特应性父母的母乳喂养儿童。