Banerjee B, Teplick S K
Department of Medicine, University of Arkansas for Medical Sciences, Little Rock 72205.
Dig Dis Sci. 1995 Mar;40(3):701-5. doi: 10.1007/BF02064393.
Forty patients with cholangiocarcinoma (23 men, 17 women) underwent nonsurgical palliative biliary drainage over a period of 12 years. All were surgically unfit or had unresectable disease. All were jaundiced at presentation with a mean serum bilirubin of 11.5 +/- 1.9 mg/dl. Thirty patients (75%) had hilar obstruction. Twenty-eight were drained percutaneously, three endoscopically and nine by a combined endoscopic and percutaneous procedure. Technical success was 97.5%. Final mean bilirubin was 1.5 +/- 0.4 mg/dl. Minor complications occurred in 10 (25%) patients, and major complications in four (10%). Procedure-related mortality was 2.5% with a 30-day mortality of 7.5%. Mean survival was 8.2 +/- 0.5 months. Stent changes were required in eight patients. In patients with inoperable or unresectable cholangiocarcinoma, percutaneous or endoscopic biliary drainage offers effective palliation.
40例胆管癌患者（23例男性，17例女性）在12年期间接受了非手术姑息性胆道引流。所有患者均不适合手术或患有不可切除的疾病。所有患者就诊时均有黄疸，平均血清胆红素为11.5±1.9mg/dl。30例患者（75%）有肝门部梗阻。28例患者接受了经皮引流，3例接受了内镜引流，9例接受了内镜和经皮联合引流。技术成功率为97.5%。最终平均胆红素为1.5±0.4mg/dl。10例患者（25%）发生轻微并发症，4例患者（10%）发生严重并发症。与操作相关的死亡率为2.5%，30天死亡率为7.5%。平均生存期为8.2±0.5个月。8例患者需要更换支架。对于无法手术或不可切除的胆管癌患者，经皮或内镜胆道引流可提供有效的姑息治疗。
