Nitric oxide in inflammation and immunity.

Few discoveries have had as comprehensive an impact on the understanding of cellular physiology as the production of nitric oxide (NO.) from the terminal guanido amino group of L-arginine through nitric oxide synthases. The sheer volume of data presently coming forth on the physiology and pathophysiology of NO. ensures that any attempt at a comprehensive review will result in a simple snapshot of the event, soon to be outdated.