Porru D, Scarpa R M, Delisa A, Usai E
Dipartimento di Scienze Chirurgiche e Trapinati d'organo, Clinica Urologica Università di Cagliari, Ospedale Santissima Trinità, Cagliari, Italia.
Eur Urol. 1994;26(4):303-8. doi: 10.1159/000475404.
Our study describes the results obtained in 44 patients with benign prostatic hyperplasia (BPH) who underwent transurethral microwave thermotherapy (TUMT) and their follow-up at 12 months. Prostatron, a prostatic TUMT device which comprised a microwave heat generator and a cooling system, was used at our centre. Forty-four out of the 60 patients given the treatment had a 12-month follow-up to be evaluated. The evaluation of subjective symptoms, according to the Boyarsky symptom score, demonstrated a significant rate of response (p < 0.0005). The analysis of pressure-flow recordings demonstrated a reduction of mean detrusor opening pressure (p < 0.0005), a reduction of detrusor pressure at maximum flow 12 months after treatment (p < 0.0005) and an improvement of mean values of maximum flow after treatment (p < 0.0005). This study shows that TUMT, though it cannot be considered an alternative to surgical or endoscopic therapy of BPH for severely obstructed patients, can produce improvement of both subjective and objective parameters of mild prostatic bladder outflow obstruction.
我们的研究描述了44例接受经尿道微波热疗(TUMT)的良性前列腺增生(BPH)患者的治疗结果及其12个月的随访情况。我们中心使用了Prostatron,这是一种前列腺TUMT设备,它由一个微波发热器和一个冷却系统组成。在接受治疗的60例患者中,有44例进行了为期12个月的随访评估。根据博亚尔斯基症状评分对主观症状进行的评估显示,有效率显著(p < 0.0005)。压力-流量记录分析显示,治疗12个月后平均逼尿肌开放压力降低(p < 0.0005),最大尿流率时的逼尿肌压力降低(p < 0.0005),治疗后最大尿流率的平均值有所改善(p < 0.0005)。这项研究表明,对于严重梗阻的患者,TUMT虽然不能被视为BPH手术或内镜治疗的替代方法,但可以改善轻度前列腺膀胱出口梗阻的主观和客观参数。