Noronha O P, Sewatkar A B, Ganatra R D
Eur J Nucl Med. 1978;3(1):47-54. doi: 10.1007/BF00253477.
Some factors, such as the effect of mannitol as 'stabilizer', increased concentration of thiosulfate, autoclaving conditions, etc., that can affect the preparation of 99mTc-sulfur colloid and consequently its biodistribution into different tissues are discussed. Also discussed are parameters, such as distribution with respect to time, effect of storage, preloading dose, etc., that can influence the uptake of the radiopharmaceutical by the RES in animals and humans.
讨论了一些可能影响99mTc-硫胶体的制备并进而影响其在不同组织中生物分布的因素，如甘露醇作为“稳定剂”的作用、硫代硫酸盐浓度增加、高压灭菌条件等。还讨论了一些参数，如随时间的分布、储存的影响、预加载剂量等，这些参数可能影响放射性药物在动物和人体中被网状内皮系统摄取。
