Krogsgaard O W
Eur J Nucl Med. 1976;1(1):31-5.
The quality of five commercial 99mTc-sulfur colloid kits was compared. A number of chemical parameters, which characterize the colloids, was used in order to study the influence of variations in the preparation procedures and storage of the final products. The differences between the kits could mainly be referred to the order of addition of the reagents. The quality was generally unaffected by variations in time-intervals during preparation. However, a certain heating time was necessary for optimal labeling. Variations in quantities of acid and buffer were found to influence the particle size as well as the content of unreacted pertechnetate. No deterioration in quality by storage was observed; on the contrary in some cases the content of free activity decreased.
比较了五种商用99mTc-硫胶体试剂盒的质量。为了研究最终产品制备程序和储存过程中变化的影响，使用了一些表征胶体的化学参数。试剂盒之间的差异主要可归因于试剂添加顺序。制备过程中的时间间隔变化通常不会影响质量。然而，为了实现最佳标记，需要一定的加热时间。发现酸和缓冲液用量的变化会影响颗粒大小以及未反应的高锝酸盐含量。未观察到储存导致质量下降；相反，在某些情况下，游离活性的含量有所降低。
