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对于身体虚弱的患者,采用单侧后外侧减压术且不进行固定,以缓解有症状的脊柱转移瘤引起的神经症状。

Unilateral posterolateral decompression without stabilization for neurological palliation of symptomatic spinal metastasis in debilitated patients.

作者信息

Weller S J, Rossitch E

机构信息

Department of Neurosurgery, Brigham and Women's Hospital/Children's Hospital, Boston, Massachusetts, USA.

出版信息

J Neurosurg. 1995 May;82(5):739-44. doi: 10.3171/jns.1995.82.5.0739.

Abstract

Patients with symptomatic spinal metastases and limited life expectancy are often too debilitated to withstand anterior or posterolateral spinal cord decompression and segmental stabilization. More limited surgery aiming solely at preservation or restoration of neurological function and relief from pain offers the potential for significant improvement in the quality of remaining life without incurring undue perioperative morbidity and mortality. Eight patients with spinal metastases and limited life expectancy underwent a unilateral transpedicular decompression procedure on their most symptomatic side and/or the side of maximum tumor involvement. All patients were neurologically improved within the 1st postoperative week; all were ambulatory and continent postoperatively. Postoperatively, all five patients with preoperative motor deficits demonstrated increased motor strength, and the three patients with predominant radicular pain reported marked improvement. There were no perioperative deaths and two transient perioperative complications. The average length of hospitalization was 6 days for patients without complications and 10 days for the entire group. Unilateral transpedicular decompression without stabilization is an effective and safe method for palliating symptomatic spinal metastases in debilitated patients with widespread malignancy and limited life expectancy. This therapeutic option should be considered in select cases as an alternative to either nonoperative management or anterior or posterolateral decompression and segmental stabilization.

摘要

有症状的脊柱转移瘤且预期寿命有限的患者往往身体过于虚弱,无法承受前路或后外侧脊髓减压及节段性稳定手术。仅旨在保留或恢复神经功能并缓解疼痛的更有限的手术,有可能显著改善剩余生命的质量,而不会带来过度的围手术期发病率和死亡率。八名预期寿命有限的脊柱转移瘤患者在其症状最明显的一侧和/或肿瘤累及最多的一侧接受了单侧经椎弓根减压手术。所有患者在术后第1周内神经功能均有改善;术后均能行走且大小便失禁。术后,术前有运动功能障碍的五名患者肌力均增强,三名以神经根性疼痛为主的患者报告疼痛明显改善。无围手术期死亡病例,有两例短暂的围手术期并发症。无并发症患者的平均住院时间为6天,全组平均住院时间为10天。单侧经椎弓根减压而不进行稳定手术是一种有效且安全的方法,可缓解患有广泛恶性肿瘤且预期寿命有限的虚弱患者的有症状脊柱转移瘤。在某些病例中,应将这种治疗选择视为非手术治疗或前路或后外侧减压及节段性稳定手术的替代方案。

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