人二倍体细胞生产的口服脊髓灰质炎疫苗（萨宾株）产量的提高。
Improvement in the yield of oral poliovirus vaccine (Sabin strains) produced in human diploid cells.
作者信息
Mirchamsy H, Shafyi S, Bahrami S, Kamali M, Nazari P, Mahinpour M
出版信息
Dev Biol Stand. 1978;41:183-5.
PMID:753650
Abstract
When stationary cultures of human diploid cells in conventional Roux bottles were replaced by the development of cells in roller bottles, the yield of poliovirus, Sabin strains type 1 and 2, showed an increase of 0.5 to 1 log10. No significant difference was noticed in the yield of these viruses cultured in WI-38 and MRC-5 human diploid cells.
摘要
当用滚瓶培养细胞取代传统鲁氏瓶中人类二倍体细胞的静止培养时，脊髓灰质炎病毒1型和2型萨宾株的产量增加了0.5至1个对数10。在WI-38和MRC-5人类二倍体细胞中培养的这些病毒的产量未发现显著差异。
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