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多发性纤维毛囊瘤(Birt-Hogg-Dubé综合征)伴巨大结缔组织痣

Multiple fibrofolliculomas (Birt-Hogg-Dubé) associated with a large connective tissue nevus.

作者信息

Weintraub R, Pinkus H

出版信息

J Cutan Pathol. 1977 Dec;4(6):289-99. doi: 10.1111/j.1600-0560.1977.tb00920.x.

DOI:10.1111/j.1600-0560.1977.tb00920.x
PMID:753849
Abstract

Multiple follicular tumors of the type recently described by Birt and colleagues as fibrofolliculomas were observed in the dorsal skin of a white man in association with a large connective tissue nevus. No signs of systemic disease or phakomatosis were present. This type of lesions represents benign neoplasia of the fibrous root sheath of the hair follicle in association with proliferations of the infundibular portion of the outer epithelial root sheath. Its existence supports the view that the mesodermal portions of the pilar apparatus can become neoplastic, and also provides another example of the close interactions existing between the ectodermal and mesodermal components of the hair follicle.

摘要

在一名白人男性的背部皮肤中,观察到多个近期被Birt及其同事描述为纤维毛囊瘤的滤泡性肿瘤,同时伴有一个大型结缔组织痣。未发现全身疾病或错构瘤的迹象。这种类型的病变代表毛囊纤维性根鞘的良性肿瘤,伴有外上皮根鞘漏斗部的增生。它的存在支持了毛囊中胚层部分可发生肿瘤的观点,也为毛囊外胚层和中胚层成分之间存在的密切相互作用提供了另一个例子。

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J Cutan Pathol. 1977 Dec;4(6):289-99. doi: 10.1111/j.1600-0560.1977.tb00920.x.
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