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复杂化学混合物的毒性:对斑马鱼(短担尼鱼)不同生命阶段的急性和长期影响。

Toxicity of complex chemical mixtures: acute and long-term effects on different life stages of zebrafish (Brachydanio rerio).

作者信息

Ensenbach U, Nagel R

机构信息

Department II, Ecotoxicology, University of Mainz, Federal Republic of Germany.

出版信息

Ecotoxicol Environ Saf. 1995 Mar;30(2):151-7. doi: 10.1006/eesa.1995.1019.

DOI:10.1006/eesa.1995.1019
PMID:7539369
Abstract

Acute and long-term toxicity of 3,4-dichloroaniline and lindane to zebrafish were examined in tap water and water from the Rhine River and the toxicity of the binary mixture 3,4-dichloroaniline/lindane in tap water was investigated. The acute toxicity of 3,4-dichloroaniline and lindane was not influenced by the complex matrix of river water compared with tap water. The binary mixture of 3,4-dichloroaniline and lindane demonstrated an additive effect in the acute test. The survival rate of early life stages in river water was reduced by lindane (80 micrograms/liter), whereas the effects of 3,4-dichloroaniline on survival and growth were visible but not significant. The binary mixture of 2 micrograms/liter, 3,4-dichloroaniline and 40 micrograms/liter lindane in tap water had an influence on growth on the early life stages of zebrafish.

摘要

研究了3,4-二氯苯胺和林丹在自来水和莱茵河水中对斑马鱼的急性和长期毒性,并调查了3,4-二氯苯胺/林丹二元混合物在自来水中的毒性。与自来水相比,3,4-二氯苯胺和林丹的急性毒性不受河水复杂基质的影响。3,4-二氯苯胺和林丹的二元混合物在急性试验中表现出相加效应。林丹(80微克/升)降低了河水中斑马鱼早期生命阶段的存活率,而3,4-二氯苯胺对存活和生长的影响虽可见但不显著。自来水中2微克/升的3,4-二氯苯胺和40微克/升的林丹二元混合物对斑马鱼早期生命阶段的生长有影响。

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