Short report: detection of 72-75-kD and 123-kD fractions of Leishmania antigen in urine of patients with visceral leishmaniasis.
作者信息
De Colmenares M, Portus M, Riera C, Gallego M, Aisa M J, Torras S, Munoz C
机构信息
Departament de Microbiologia i Parasitologia Sanitaries, Facultat de Farmacia, Universitat de Barcelona, Spain.
出版信息
Am J Trop Med Hyg. 1995 May;52(5):427-8. doi: 10.4269/ajtmh.1995.52.427.
PMID:7539596
Abstract
Two polypeptide fractions of 72-75 kD were detected in the urine of 14 of 15 patients with visceral leishmaniasis (VL) and another fraction of 123 kD was found in 10 of the 15 patients by using a Western blot technique. None of these fractions was detected in the urine of 20 controls. These results suggest that antigen detection in urine could be a powerful, noninvasive method for VL diagnosis.
摘要
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