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胸膜内注射米托蒽醌用于恶性胸腔积液的姑息治疗。

Intrapleural mitoxantrone for the palliative treatment of malignant pleural effusions.

作者信息

Morales M, Expósito M C

机构信息

Department of Medicine, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Canary Islands, Spain.

出版信息

Support Care Cancer. 1995 Mar;3(2):147-9. doi: 10.1007/BF00365856.

DOI:10.1007/BF00365856
PMID:7539702
Abstract

A group of 21 patients with malignant pleural effusions were treated with the instillation of 40 mg mitoxantrone intrapleurally, after complete fluid drainage. There was a 100% complete response rate with no toxic effects (0%). The mean survival of the patients was 57.1 weeks.

摘要

一组21例恶性胸腔积液患者在胸腔积液完全引流后，经胸腔内注入40毫克米托蒽醌进行治疗。完全缓解率为100%，且无毒性反应（0%）。患者的平均生存期为57.1周。

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Intrapleural palliative treatment of malignant pleural effusions with mitoxantrone versus placebo (pleural tube alone).米托蒽醌与安慰剂（仅胸腔引流管）治疗恶性胸腔积液的胸膜内姑息治疗对比
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