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美国前列腺癌诊断与管理的实践趋势

Practice trends in the diagnosis and management of prostate cancer in the United States.

作者信息

Gee W F, Holtgrewe H L, Albertsen P C, Litwin M S, Manyak M J, O'Leary M P, Painter M R

机构信息

Health Policy Survey and Research Committee, American Urological Association, Baltimore, Maryland, USA.

出版信息

J Urol. 1995 Jul;154(1):207-8.

PMID:7539862
Abstract

PURPOSE

The American Urological Association first commissioned the Gallup Organization of Princeton, New Jersey to conduct a study to assess urologists' practice patterns in 1991.

MATERIALS AND METHODS

A random sample of 514 American urologists was surveyed by the Gallup Organization regarding practice patterns used in the staging and treatment of prostate cancer. The third annual survey taken during August 1994 asked questions regarding the practice of respondents in their diagnosis and management of prostatic cancer.

RESULTS

The survey revealed that 95% of the respondents would recommend radical prostatectomy for men younger than 70 years with confirmed clinically localized prostate cancer.

CONCLUSIONS

In this patient age group, surprisingly, the survey resulted in some interesting facts: 1) 13% regard hormonal manipulation for early stage cancer appropriate, 2) the respondents used extensive numbers of diagnostic staging studies in the new prostate cancer patient with a prostate specific antigen of less than 10 and 3) despite the obvious increased costs, the majority of patients receiving hormone manipulation were being treated with luteinizing hormone-releasing hormone agonists rather than orchiectomy.

摘要

目的

1991年,美国泌尿外科学会首次委托新泽西州普林斯顿的盖洛普民意调查机构开展一项研究,以评估泌尿科医生的执业模式。

材料与方法

盖洛普民意调查机构对514名美国泌尿科医生进行随机抽样调查,了解他们在前列腺癌分期和治疗中所采用的执业模式。1994年8月进行的第三次年度调查询问了受访者在前列腺癌诊断和管理方面的执业情况。

结果

调查显示,95%的受访者会建议对确诊为临床局限性前列腺癌的70岁以下男性进行根治性前列腺切除术。

结论

在这个患者年龄组中,令人惊讶的是,调查得出了一些有趣的事实:1)13%的人认为对早期癌症进行激素治疗是合适的;2)受访者对前列腺特异性抗原低于10的新前列腺癌患者进行了大量的诊断分期研究;3)尽管成本明显增加,但大多数接受激素治疗的患者使用的是促黄体生成素释放激素激动剂,而非睾丸切除术。

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J Natl Cancer Inst. 2006 Jun 21;98(12):839-45. doi: 10.1093/jnci/djj230.
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Androgen deprivation and cognition in prostate cancer.前列腺癌中的雄激素剥夺与认知
Br J Cancer. 2003 Sep 15;89(6):971-6. doi: 10.1038/sj.bjc.6601235.
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The economic costs of early stage prostate cancer.早期前列腺癌的经济成本。
Pharmacoeconomics. 2002;20(13):869-78. doi: 10.2165/00019053-200220130-00001.