Nisolle M, Casanas-Roux F, Donnez J
Department of Gynecology, Catholic University of Louvain, St. Luc Hospital, Brussels, Belgium.
Fertil Steril. 1995 Jul;64(1):69-75.
To evaluate quantitatively cytokeratin and vimentin staining in glandular and stromal cells of eutopic and ectopic endometrium.
The investigation of cytokeratin and vimentin was carried out using the new computerized technology of image analysis.
University Hospital, Department of Gynecology.
Biopsies were taken from patients undergoing a laparoscopy for infertility (29 endometrial biopsies and 31 biopsies of peritoneal endometriosis). None of them were treated.
Cyclic variations of cytokeratin and vimentin staining were noted in eutopic endometrium. The cytokeratin and vimentin staining pattern consistently was lower in ectopic endometrium than in eutopic endometrium.
Endometriotic epithelial and stromal cells undergo a complex program of differentiation giving them histochemical characteristics similar to those observed in endometrium. Such a concomitant expression of antigenicity indicates their close relationship with their mesodermal müllerian origin.
定量评估在位和异位子宫内膜的腺细胞和基质细胞中细胞角蛋白和波形蛋白的染色情况。
采用新的计算机图像分析技术对细胞角蛋白和波形蛋白进行研究。
大学医院妇产科。
对因不孕症接受腹腔镜检查的患者进行活检（29例子宫内膜活检和31例腹膜子宫内膜异位症活检）。所有患者均未接受治疗。
在位子宫内膜中细胞角蛋白和波形蛋白染色呈现周期性变化。异位子宫内膜中细胞角蛋白和波形蛋白的染色模式始终低于在位子宫内膜。
子宫内膜异位症的上皮细胞和基质细胞经历复杂的分化过程，使其具有与子宫内膜相似的组织化学特征。这种抗原性的伴随表达表明它们与其中胚层苗勒氏起源密切相关。
