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Regulation of development, survival and neoplastic growth of mast cells through the c-kit receptor.

作者信息

Kitamura Y, Tsujimura T, Jippo T, Kasugai T, Kanakura Y

机构信息

Department of Pathology, Osaka University Medical School, Japan.

出版信息

Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):54-6. doi: 10.1159/000236929.

Abstract

Signaling through the c-kit receptor tyrosine kinase (Kit) is essential for development and survival of mast cells but not of basophils. Moreover, we recently found an activation mutation of Kit in several tumor mast cell lines.

摘要

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