Kitamura Y, Tsujimura T, Jippo T, Kasugai T, Kanakura Y
Department of Pathology, Osaka University Medical School, Japan.
Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):54-6. doi: 10.1159/000236929.
Signaling through the c-kit receptor tyrosine kinase (Kit) is essential for development and survival of mast cells but not of basophils. Moreover, we recently found an activation mutation of Kit in several tumor mast cell lines.