Bischoff P M, Niederberger H J, Török B, Speiser P
Department of Ophthalmology, Kantonsspital, St. Gallen, Switzerland.
Retina. 1995;15(2):91-9. doi: 10.1097/00006982-199515020-00002.
To facilitate the interpretation of the choroidal dye filling sequence, the use of simultaneous indocyanine green (ICG) and fluorescein angiography was evaluated.
A single-wavelength scanning laser ophthalmoscope (SLO) was modified to a two-wavelength system, permitting the simultaneous recording of ICG and fluorescein angiography. This method has been used in 340 cases. About two thirds of the patients had well-defined or occult choroidal neovascularization (CNV) in age-related macular degeneration (AMD).
Simultaneous ICG and fluorescein angiography is feasible with a two-wavelength SLO and provides images of good quality. Two corresponding ICG and fluorescein angiography pictures can be presented as one combined red-green picture.
This method has three advantages: (1) it allows a precise comparison of the transit of both dyes through both circulations, and there are no differences in the injected bolus nor in the actual blood pressure; (2) the important features of the ICG angiograms are fully aligned with the critical retinal vascular landmarks provided by the fluorescein images; and (3) it is very time efficient--with a single injection and one photographic session, immediate results are obtained.
为便于解读脉络膜染料充盈顺序，对同步使用吲哚菁绿（ICG）和荧光素血管造影进行了评估。
将单波长扫描激光检眼镜（SLO）改装为双波长系统，从而能够同步记录ICG和荧光素血管造影。该方法已应用于340例患者。约三分之二的患者在年龄相关性黄斑变性（AMD）中存在明确或隐匿性脉络膜新生血管（CNV）。
使用双波长SLO同步进行ICG和荧光素血管造影是可行的，并且能提供高质量图像。两张相应的ICG和荧光素血管造影图片可呈现为一张红绿组合图片。
该方法具有三个优点：（1）它能精确比较两种染料在两种循环中的通过情况，注射团注量和实际血压均无差异；（2）ICG血管造影片的重要特征与荧光素图像提供的关键视网膜血管标志完全对齐；（3）非常省时——单次注射和一次摄影即可立即获得结果。
