核糖核蛋白结构域：一个参与RNA加工和运输的序列特异性RNA结合结构域。
The RNP domain: a sequence-specific RNA-binding domain involved in processing and transport of RNA.
作者信息
Nagai K, Oubridge C, Ito N, Avis J, Evans P
机构信息
MRC Laboratory of Molecular Biology, Cambridge, UK.
出版信息
Trends Biochem Sci. 1995 Jun;20(6):235-40. doi: 10.1016/s0968-0004(00)89024-6.
PMID:7543225
Abstract
The RNP domain is found in a number of proteins involved in processing and transport of mRNA precursors. The crystal structure of a complex between the U1A spliceosomal protein and its cognate RNA hairpin at 1.92 A resolution reveals the molecular basis of sequence-specific RNA recognition by the RNP domain.
摘要
RNP结构域存在于许多参与mRNA前体加工和运输的蛋白质中。U1A剪接体蛋白与其同源RNA发夹形成的复合物的晶体结构，分辨率为1.92埃，揭示了RNP结构域对序列特异性RNA识别的分子基础。
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