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[对动物进行的硫酸锌和泛酸盐的急性毒性及致溃疡能力的比较(作者译)]

[Comparison of the acute toxicity and the ulcer inducing power of zinc sulphate and pantothenate carried out in animals (author's transl)].

作者信息

Courtois P, Guillard O, Pouyollon M, Piriou A, Warnet J M

出版信息

Toxicol Eur Res. 1978 Nov;1(6):371-3.

PMID:754349
Abstract

Zinc sulphate and pantothenate are two drugs capable of inducing ulcer. An experimental was performed in order to determine the acute toxicity of both drugs. The obtained data were in favour of a lesser ulcer inducing capacity of zinc pantothenate, associated to a better diffusion of this salt in the peripheral tissues. These results suggest a plausible use of zinc pantothenate as a therapeutic agent.

摘要

硫酸锌和泛酸钙是两种能够诱发溃疡的药物。为了确定这两种药物的急性毒性,进行了一项实验。所获得的数据表明泛酸锌诱发溃疡的能力较小,这与该盐在周围组织中更好的扩散有关。这些结果表明泛酸锌作为一种治疗剂有合理的应用前景。

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