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Transcription factors NF-IL6 and APRF involved in gp130-mediated signaling pathway.

作者信息

Akira S, Nishio Y, Tanaka T, Inoue M, Matsusaka T, Wang X J, Wei S, Yoshida N, Kishimoto T

机构信息

Institute for Molecular and Cellular Biology, Osaka University, Japan.

出版信息

Ann N Y Acad Sci. 1995 Jul 21;762:15-27; discussion 27-8. doi: 10.1111/j.1749-6632.1995.tb32310.x.

DOI:10.1111/j.1749-6632.1995.tb32310.x
PMID:7545362
Abstract
摘要

相似文献

1
Transcription factors NF-IL6 and APRF involved in gp130-mediated signaling pathway.
Ann N Y Acad Sci. 1995 Jul 21;762:15-27; discussion 27-8. doi: 10.1111/j.1749-6632.1995.tb32310.x.
2
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway.APRF的分子克隆,APRF是一种新型的干扰素刺激基因因子3 p91相关转录因子,参与gp130介导的信号通路。
Cell. 1994 Apr 8;77(1):63-71. doi: 10.1016/0092-8674(94)90235-6.
3
Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation.通过白细胞介素6信号转导子gp130的胞质结构域对急性期反应因子/信号转导和转录激活因子3(Stat3)及信号转导和转录激活因子1(Stat1)的差异性激活。II. Src同源SH2结构域决定信号转导和转录激活因子激活的特异性。
J Biol Chem. 1996 May 31;271(22):12999-3007. doi: 10.1074/jbc.271.22.12999.
4
Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.转录因子APRF和蛋白激酶Jak1与白细胞介素-6信号转导子gp130的关联。
Science. 1994 Jan 7;263(5143):89-92. doi: 10.1126/science.8272872.
5
Membrane-bound and soluble interleukin-6 receptor: studies on structure, regulation of expression, and signal transduction.
Ann N Y Acad Sci. 1995 Jul 21;762:222-36; discussion 236-7. doi: 10.1111/j.1749-6632.1995.tb32328.x.
6
Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation.通过白细胞介素6信号转导子gp130的胞质结构域对急性期反应因子/信号转导子和转录激活子3(STAT3)及信号转导子和转录激活子1(STAT1)的差异性激活。I. 介导STAT1激活的新型磷酸酪氨酸基序的定义。
J Biol Chem. 1996 May 31;271(22):12991-8. doi: 10.1074/jbc.271.22.12991.
7
TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.肿瘤坏死因子-α诱导酪氨酸磷酸化,并使Src同源蛋白酪氨酸磷酸酶2募集至白细胞介素-6受体复合物的gp130信号转导亚基。
J Immunol. 2003 Jul 1;171(1):257-66. doi: 10.4049/jimmunol.171.1.257.
8
Signal transduction through homo- or heterodimers of gp130.通过gp130同二聚体或异二聚体的信号转导。
Stem Cells. 1994;12 Suppl 1:37-44; discussion 44-5.
9
Signal transduction through IL-6 receptor: involvement of multiple protein kinases, stat factors, and a novel H7-sensitive pathway.
Ann N Y Acad Sci. 1995 Jul 21;762:55-70. doi: 10.1111/j.1749-6632.1995.tb32314.x.
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Structure and function of a new STAT-induced STAT inhibitor.一种新型STAT诱导的STAT抑制剂的结构与功能
Nature. 1997 Jun 26;387(6636):924-9. doi: 10.1038/43219.

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Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the -174 IL-6 G/C polymorphism in children.
肠道炎症诱导的生长迟缓在大鼠中通过白细胞介素-6起作用,而在儿童中则取决于白细胞介素-6基因-174位点G/C多态性。
Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13260-5. doi: 10.1073/pnas.0503589102. Epub 2005 Sep 6.
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STAT1 binds to the herpes simplex virus type 1 latency-associated transcript promoter.信号转导和转录激活因子1(STAT1)与1型单纯疱疹病毒潜伏相关转录物启动子结合。
J Neurovirol. 2004 Feb;10(1):12-20. doi: 10.1080/13550280490261680.
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The lipopolysaccharide-binding protein is a secretory class 1 acute-phase protein whose gene is transcriptionally activated by APRF/STAT/3 and other cytokine-inducible nuclear proteins.脂多糖结合蛋白是一种分泌型1类急性期蛋白,其基因由APRF/STAT/3和其他细胞因子诱导的核蛋白转录激活。
Mol Cell Biol. 1996 Jul;16(7):3490-503. doi: 10.1128/MCB.16.7.3490.