Schwartz R A
New Jersey Medical School, Newark 07103-2714, USA.
J Am Acad Dermatol. 1995 Oct;33(4):649-57. doi: 10.1016/0190-9622(95)91288-6.
In cutaneous metastatic disease the histologic pattern may be specific or nonspecific. Carcinoma cutis most often shows only the nonspecific pattern of an adenocarcinoma, a squamous cell carcinoma, or an undifferentiated metastatic tumor. However, certain clinical and histologic characteristics may suggest a primary tumor site and type. In addition, special histologic stains and the use of immunohistochemical and electronmicroscopic techniques may also prove valuable in the diagnosis of carcinoma cutis and other cutaneous metastatic diseases.
在皮肤转移性疾病中,组织学模式可能是特异性的或非特异性的。皮肤癌最常仅表现为腺癌、鳞状细胞癌或未分化转移性肿瘤的非特异性模式。然而,某些临床和组织学特征可能提示原发性肿瘤的部位和类型。此外,特殊的组织学染色以及免疫组织化学和电子显微镜技术的应用在皮肤癌和其他皮肤转移性疾病的诊断中也可能具有重要价值。