Yamada H, Ide A, Sugiura M, Kurihara S, Tajima S
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
J Dermatol. 1995 May;22(5):354-6. doi: 10.1111/j.1346-8138.1995.tb03403.x.
Three cases of granuloma annulare which did not exhibit a self-limited course were treated with tranilast at the dose of 300 mg/daily. The treatment resulted in the resolution of skin lesions within three months of administration. Although spontaneous resolution is often observed in granuloma annulare, tranilast may provide an alternative therapy for the treatment of cases resistant to spontaneous healing.
3例未表现出自限性病程的环状肉芽肿患者接受了曲尼司特治疗，剂量为每日300毫克。治疗导致皮损在给药后三个月内消退。虽然环状肉芽肿常可见自发消退，但曲尼司特可为治疗对自发愈合有抵抗的病例提供一种替代疗法。
