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人类核糖体蛋白L37具有预测丝氨酸/苏氨酸磷酸化的基序和一个锌指结构域。

Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain.

作者信息

Barnard G F, Staniunas R J, Puder M, Steele G D, Chen L B

机构信息

Division of Cellular and Molecular Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.

出版信息

Biochim Biophys Acta. 1994 Aug 2;1218(3):425-8. doi: 10.1016/0167-4781(94)90197-x.

Abstract

Ribosomal protein L37 mRNA is overexpressed in colon cancer. The nucleotide sequences of human L37 from several tumor and normal, colon and liver cDNA sources were determined to be identical. L37 mRNA was approximately 375 nucleotides long encoding 97 amino acids with M(r) = 11,070, pI = 12.6, multiple potential serine/threonine phosphorylation sites and a zinc-finger domain. The human sequence is compared to other species.

摘要

核糖体蛋白L37 mRNA在结肠癌中过表达。已确定来自几种肿瘤及正常结肠和肝脏cDNA来源的人L37核苷酸序列是相同的。L37 mRNA约375个核苷酸长,编码97个氨基酸,分子量为11,070,等电点为12.6,有多个潜在的丝氨酸/苏氨酸磷酸化位点和一个锌指结构域。将人类序列与其他物种进行了比较。

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