Nucleotide and deduced amino acid sequence of human ribosomal protein L18.
作者信息
Puder M, Barnard G F, Staniunas R J, Steele G D, Chen L B
机构信息
Division of Cellular and Molecular Biology, Dana-Farber Cancer Institute Harvard Medical School, Boston, MA.
出版信息
Biochim Biophys Acta. 1993 Oct 19;1216(1):134-6. doi: 10.1016/0167-4781(93)90050-n.
PMID:8218404
Abstract
Ribosomal protein L18 mRNA is overexpressed in human colorectal cancer compared to normal colon tissue. We report the nucleotide sequence of human L18 cDNA derived from a normal colon source. There were no mutational changes in segments of L18 cDNA derived from two tumor sources. The L18 cDNA was 690 base pairs long and predicts a single open reading frame of 564 nucleotides, encoding 188 amino acids with a M(r) = 21,621, it is homologous to rat L18 and Xenopus laevis L14.
摘要
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