保幼激素类似物（JHA）对克氏锥虫发育的影响。
Effects of juvenile hormone analogues (JHA) on the development of Trypanosoma cruzi.
作者信息
Fichera L, Esteva M, Wimmer Z, Rodriguez J B, Gros E G
机构信息
Instituto Nacional de Chagas, Buenos Aires, Argentina.
出版信息
Z Naturforsch C J Biosci. 1995 Jul-Aug;50(7-8):578-80. doi: 10.1515/znc-1995-7-817.
PMID:7546047
Abstract
Juvenile hormone analogues were tested for their lytic activity on Trypanosoma cruzi Chagas, 1909 blood tripomastigotes cultivated in vitro. The results indicated that the carbamate 4 and the phenoxyphenol derivative 1 are considered good candidates for blood sterilization. The compounds were also assayed for inhibition of development of parasites in infected mice showing a moderated degree of activity.
摘要
对保幼激素类似物针对1909年发现的克氏锥虫血液型锥鞭毛体在体外培养时的裂解活性进行了测试。结果表明，氨基甲酸酯4和苯氧基苯酚衍生物1被认为是血液消毒的良好候选物。还对这些化合物在受感染小鼠体内抑制寄生虫发育的情况进行了测定，结果显示其活性程度适中。
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