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乙酰唑胺治疗出血性卒中的疗效评估

Acetazolamide therapy evaluation in haemorrhagic stroke.

作者信息

Popa G, Amaireh M, Dinu M, Jipescu I, Alaicescu M, Stănescu A, Nistorescu A

机构信息

Institute of Neurology and Psychiatry, G. Marinescu Hospital.

出版信息

Rom J Neurol Psychiatry. 1995 Apr-Jun;33(2):145-55.

PMID:7547378
Abstract

The influence of acetazolamide in patients with hemorrhagic stroke was assessed in 54 patients in comparison with the influence of other therapies in 68 patients included in a control group. Modified Rankin Scale and mortality rate were evaluated at three different moments: onset, 72 hours and control (3 weeks-one month from the onset). A better outcome was seen when acetazolamide was given. Mortality rate was significantly lower in the group of acetazolamide. This therapy may be safely used in haemorrhagic stroke, especially when hydrocephalus is associated.

摘要

在54例患者中评估了乙酰唑胺对出血性中风患者的影响,并与68例纳入对照组的患者接受其他疗法的影响进行了比较。在三个不同时间点评估改良Rankin量表和死亡率:发病时、72小时和对照期(发病后3周 - 1个月)。给予乙酰唑胺时观察到更好的结果。乙酰唑胺组的死亡率显著更低。这种疗法可安全用于出血性中风,尤其是伴有脑积水的情况。

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Acetazolamide therapy evaluation in haemorrhagic stroke.乙酰唑胺治疗出血性卒中的疗效评估
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Acetazolamide is an effective adjunct for urinary alkalization in patients with uric acid and cystine stone formation recalcitrant to potassium citrate.乙酰唑胺是一种有效的辅助药物,用于对枸橼酸钾治疗无效的尿酸和胱氨酸结石形成患者的尿液碱化。
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