Picornell A, Castro J A, Ramon M M
Dept. de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Blears, Spain.
Gene Geogr. 1994 Aug;8(2):137-45.
A sample of 140 Chuetas (descendants of Majorcan Jews) were typed for the GC, A2HS, ORM, ITI and HP serum proteins. Studies on ORM and ITI markers have not yet been reported in other Jewish populations. The allele frequencies obtained were: GC1 = 0.610; A2HS1 = 0.787; ORMF1 = 0.339; ORMS = 0.497; ITI1 = 0.581; ITI2 = 0.414; HP2FS = 0.625; HP1S = 0.230; HP1F = 0.135. Some rare variants were found in polymorphic frequencies (ORMS1 = 0.043; ORMSS2 = 0.096; A2HS10 = 0.015). These results have been compared with those found in other Jewish and non-Jewish European populations. The relatively high frequency of the HP2FS allele and the presence of ORMS1 and ORM*S2 variants in Chuetas show the Jewish origin of this population. The frequencies of GC and A2HS in Chuetas are similar to those found in other surrounding non-Jewish populations. ITI results are similar to those found in the two European populations studied. HP frequencies suggest a Spanish admixture.
对140名楚埃塔人（马略卡岛犹太人的后裔）的GC、A2HS、ORM、ITI和HP血清蛋白进行了分型。在其他犹太人群体中尚未有关于ORM和ITI标记的研究报道。获得的等位基因频率如下：GC1 = 0.610；A2HS1 = 0.787；ORMF1 = 0.339；ORMS = 0.497；ITI1 = 0.581；ITI2 = 0.414；HP2FS = 0.625；HP1S = 0.230；HP1F = 0.135。在多态频率中发现了一些罕见变体（ORMS1 = 0.043；ORMS2 = 0.096；A2HS10 = 0.015）。已将这些结果与在其他犹太和非犹太欧洲人群体中发现的结果进行了比较。楚埃塔人中HP2FS等位基因的相对高频率以及ORMS1和ORM*S2变体的存在表明了该人群的犹太起源。楚埃塔人中GC和A2HS的频率与在其他周边非犹太人群体中发现的频率相似。ITI的结果与在两个被研究的欧洲人群体中发现的结果相似。HP频率表明有西班牙人血统。
