原发性开角型青光眼与正常眼压性青光眼眼动脉血流速度的比较。
Comparison of flow velocity of ophthalmic artery between primary open angle glaucoma and normal tension glaucoma.
作者信息
Yamazaki Y, Hayamizu F
机构信息
Department of Ophthalmology, Nihon University School of Medicine, Tokyo, Japan.
出版信息
Br J Ophthalmol. 1995 Aug;79(8):732-4. doi: 10.1136/bjo.79.8.732.
AIMS
This study describes an investigation of the relation between the change of intraocular circulatory dynamics and visual field defect between primary open angle glaucoma (POAG) and normal tension glaucoma (NTG).
METHODS
The method was to determine the blood flow velocity of the ophthalmic artery using colour Doppler imaging and quantitative peak systolic flow velocity, mean envelope velocity, end diastolic velocity, and Pourcelot resistivity index (RI) were determined. The visual field was examined using program 30-2 of the Humphrey field analyser: the mean deviation (MD) and corrected pattern standard deviation (CPSD) were calculated as indices for visual field defects. There were 25 patients with POAG and 25 patients with NTG.
RESULTS
There were no significant differences in all the four indices of the ophthalmic arterial flow and in both of visual field indices between patients with POAG and those with NTG. However, NTG patients alone showed a statistically significant correlation between RI and MD.
CONCLUSION
The results suggest the vascular resistance of the ophthalmic artery may be associated with the development of visual field defect in NTG patients.
目的
本研究描述了一项关于原发性开角型青光眼（POAG）和正常眼压性青光眼（NTG）患者眼内循环动力学变化与视野缺损之间关系的调查。
方法
采用彩色多普勒成像测定眼动脉血流速度，并测定定量峰值收缩期流速、平均包络速度、舒张末期速度和普尔塞洛阻力指数（RI）。使用汉弗莱视野分析仪的30-2程序检查视野：计算平均偏差（MD）和校正模式标准差（CPSD）作为视野缺损的指标。POAG患者25例，NTG患者25例。
结果
POAG患者和NTG患者的眼动脉血流的所有四个指标以及两个视野指标均无显著差异。然而，仅NTG患者的RI与MD之间存在统计学上的显著相关性。
结论
结果表明眼动脉的血管阻力可能与NTG患者视野缺损的发生有关。
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