Morgan R J, Pryor J P
Br J Urol. 1978 Apr;50(2):111-3. doi: 10.1111/j.1464-410x.1978.tb03038.x.
Thirty-four men with Peyronie's diseases were treated with a 12-week course of the drug procarbazine (Natulan), preceded or followed by a 12-week course of vitamin E. Ninety-one per cent of the men failed to improve or became worse whilst receiving Natulan and toxic side-effects were common. In comparison 39% improved whilst taking vitamin E. We concluded that Natulan is of little benefit in the treatment of this condition and may indeed be harmful.
34名患有佩罗尼氏病的男性接受了为期12周的丙卡巴肼（纳治兰）治疗疗程，该疗程之前或之后接受为期12周的维生素E疗程。91%的男性在接受纳治兰治疗期间病情未改善或恶化，且常见毒性副作用。相比之下，39%的男性在服用维生素E期间病情有所改善。我们得出结论，纳治兰对治疗这种疾病益处不大，甚至可能有害。
