[哥伦比亚亚马逊地区一种新型抗蠕虫药氟苯达唑的治疗试验]
[Therapeutic trials of a new anti-helminthic in Colombian Amazonia: flubendazole].
作者信息
Penot C, Picot H, Lavarde V
出版信息
Bull Soc Pathol Exot Filiales. 1978 Jul-Oct;71(4-5):370-5.
After a coprologic survey made at Araracuara, a village in colombian Amazonia showing high prevalences of nematodosis, 83 villages (including 55 children below twelve) were given Flubendazole during three consecutive days. The total dose was 600 mg. for children below 12, and 900 mg. for adults. The product efficiency was 88% for Trichuris, 82% for Hookworm, 77% for Ascaris and 43% for Strongyloïdes. The tolerance was excellent in all cases, in spite of heavy parasital infection. The Flubendazole's effect seems to be particularly interesting by its polyvalency.
在对哥伦比亚亚马逊地区一个线虫病高流行率的村庄阿拉拉夸拉进行粪便学调查后，连续三天为83个村庄（包括55名12岁以下儿童）提供了氟苯达唑。12岁以下儿童的总剂量为600毫克，成人的总剂量为900毫克。该产品对鞭虫的疗效为88%，对钩虫为82%，对蛔虫为77%，对粪类圆线虫为43%。尽管寄生虫感染严重，但在所有病例中耐受性都非常好。氟苯达唑的作用因其多效性似乎特别有趣。
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