[阿苯达唑。对蛲虫病、鞭虫病、钩虫病、蛔虫病、粪类圆线虫病的耐受性及疗效评估]

[Albendazole. Evaluation of tolerance and efficacy in oxyuriasis, trichocephaliasis, ankylostomiasis, ascaridiasis, anguilluliasis].

作者信息

Maisonneuve H, Piens M A, Mojon M, Garin J P

出版信息

Bull Soc Pathol Exot Filiales. 1981 Jul-Aug;74(4):434-44.

Abstract

Albendazole was given to some men for the first time. 131 patients (43 children) received different dosages, without clinical intolerance. Biological parameters were normal. Each study was made in two parts: - determination of the good dosage, - administration in a double-blind study (except for Strongyloides Stercoralis). Albendazole has a good efficiency against Enterobius Vermicularis, Trichuris trichiura, Ascaris lumbricoides and Necator americanus. Strongyloides Stercoralis seems to be killed by this drug, but complementary studies will be necessary.

摘要

阿苯达唑首次应用于部分男性。131名患者（43名儿童）接受了不同剂量的阿苯达唑，未出现临床不耐受情况。生物学参数正常。每项研究分为两个部分：- 确定合适剂量，- 进行双盲研究给药（粪类圆线虫除外）。阿苯达唑对蛲虫、鞭虫、蛔虫和美洲钩虫具有良好疗效。粪类圆线虫似乎可被该药杀灭，但仍需进一步研究。