Callea F, Baronchelli C, Rodolfi A, Bonetti M F, Brisigotti M
Divisione di Patologia, Spedali Civili di Brescia, Italy.
Ital J Gastroenterol. 1995 Apr;27(3):137-40.
Over the last few years a need for reassessment of the classification of chronic hepatitis has emerged in both clinicians who diagnose and treat liver patients and histopathologists who evaluate liver biopsies. The introduction of an aetiologic terminology, the evaluation of inflammatory activity and necrosis (grading) as well as of fibrosis as the equivalents of a stage in the disease appear to be major requirements. Due to the present satisfactory knowledge of the natural history of hepatitis B, there is also a discussion on the advisability of a personalized classification of chronic hepatitis B, i.e. a classification based upon consideration of profiles (or phases) rather than rigid morphological categories. This paper is intended as a guideline with a view to a revised classification of chronic hepatitis.
在过去几年中，无论是诊断和治疗肝病患者的临床医生，还是评估肝活检的组织病理学家，都出现了重新评估慢性肝炎分类的需求。引入病因学术语、评估炎症活动和坏死（分级）以及评估纤维化作为疾病阶段的等效指标，似乎是主要要求。由于目前对乙型肝炎自然史有了令人满意的了解，因此也在讨论对慢性乙型肝炎进行个性化分类的可取性，即基于对特征（或阶段）而非严格形态学类别的考虑进行分类。本文旨在作为慢性肝炎修订分类的指南。
