Neamţu A, Cozgarea R, State D, Neamţu D
Universitatea de Medicină şi Farmacie, Cluj-Napoca.
Bacteriol Virusol Parazitol Epidemiol. 1995 Apr-Jun;40(2):115-8.
Recently, hepatitis C virus (HCV) have been recognised as being one of the most important cause of non-A, non-B hepatitis. Although parenteral transmission of HCV is wellknown, the risk of sexual transmission is still under debate.
This study was conducted to assess the HCV infection markers in sexually transmitted disease (STD) patients from an endemic area for hepatitis B virus (HBV) infection. Additionally, we studied the prevalence of HBV infection markers in these patients.
The sera of 121 patients with STD from Cluj-Napoca have been tested for antibodies to HCV (anti-HCV), Hbs antigen (Hbs Ag), antibodies to Hbc antigen (anti-HBc), by automated ELISA.
Anti-HCV were detected in 26/121 (21.5%) patients: 73/121 (60.3%) patients presented HBV infection markers HBV infection markers (HbsAg and or anti-HBc) have been observed in 22/26 (84.6%) HCV infected patients.
Prevalence of HCV infection markers in STD patients from Cluj is high (21.5%). HBV infection markers have been detected in 60.3% of patients. In STD patients form Cluj HCV infection markers have been correlated to HBV infection markers.
最近，丙型肝炎病毒（HCV）已被公认为是非甲非乙型肝炎的最重要病因之一。虽然HCV的肠道外传播已广为人知，但其性传播风险仍存在争议。
本研究旨在评估来自乙型肝炎病毒（HBV）感染流行地区的性传播疾病（STD）患者中的HCV感染标志物。此外，我们还研究了这些患者中HBV感染标志物的流行情况。
采用自动酶联免疫吸附测定法（ELISA）对来自克卢日-纳波卡的121例STD患者的血清进行了HCV抗体（抗-HCV）、乙肝表面抗原（Hbs Ag）、乙肝核心抗原抗体（抗-HBc）检测。
121例患者中有26例（21.5%）检测到抗-HCV；121例患者中有73例（60.3%）呈现HBV感染标志物；在26例HCV感染患者中，有22例（84.6%）观察到HBV感染标志物（HbsAg和/或抗-HBc）。
克卢日STD患者中HCV感染标志物的流行率较高（21.5%）。60.3%的患者检测到HBV感染标志物。在克卢日的STD患者中，HCV感染标志物与HBV感染标志物相关。
