Neamţu A, Pascu O, Szanto P, Chira O, Neamţu D, State D
Universitatea de Medicină şi Farmacie, Cluj-Napoca.
Bacteriol Virusol Parazitol Epidemiol. 1995 Apr-Jun;40(2):119-23.
We studied the prevalence of viral hepatitis B, C and D markers in chronic hepatopathies from Cluj.
Sera of 297 patients with chronic hepatopathies (236 adults and 61 children) have been tested for viral hepatitis markers: HBsAg, anti-HBc, anti-HBs, HBeAg, anti-HBe, anti-HDV, anti-HCV, by automated ELISA.
HBV infection markers in 32% (adults) and 4.9% (children), and HDV infection markers in 11.8% (adults) and 26.3% (children). Double (HBV and HCV) and triple infection (HBV, HDV and HCV) were observed in 28.4% (adults), 4.9% (children), and 3.4% (adults), 0% (children), respectively.
Hepatitis virus infection markers, especially HBV and HCV play an important role in the determinism of chronic hepatopathies from Cluj area, both in children and adults.
我们研究了克卢日慢性肝病患者中乙型、丙型和丁型病毒性肝炎标志物的流行情况。
采用自动酶联免疫吸附测定法，对297例慢性肝病患者（236例成人和61例儿童）的血清进行病毒性肝炎标志物检测：乙肝表面抗原（HBsAg）、乙肝核心抗体（抗-HBc）、乙肝表面抗体（抗-HBs）、乙肝e抗原（HBeAg）、乙肝e抗体（抗-HBe）、丁肝抗体（抗-HDV）、丙肝抗体（抗-HCV）。
成人中乙肝病毒（HBV）感染标志物阳性率为32%，儿童为4.9%；成人中丁肝病毒（HDV）感染标志物阳性率为11.8%，儿童为26.3%。成人中HBV和HCV双重感染率为28.4%，儿童为4.9%；成人中HBV、HDV和HCV三重感染率为3.4%，儿童为0%。
肝炎病毒感染标志物，尤其是HBV和HCV，在克卢日地区儿童和成人慢性肝病的发病机制中起着重要作用。
