β2-微球蛋白与葡萄球菌蛋白A反应失败。
Failure of the reaction of beta2-microglobulin with staphylococcal protein A.
作者信息
Ochi Y, Hachiya T, Kajita Y
出版信息
Microbiol Immunol. 1977 Nov;21(11):649-52. doi: 10.1111/j.1348-0421.1977.tb00333.x.
Abstract
Because beta2-microglobulin is structurally similar to IgG, the reaction of beta2-microglobulin with Staphylococcal Protein A, which is known to react with the Fc region of IgG, was examined. 125I-beta2-microglobulin did not bind to Protein A. This may due to the difference in the amino acid sequence between beta2-microglobulin and the Fc region of IgG.
摘要
由于β2-微球蛋白在结构上与免疫球蛋白G（IgG）相似，因此研究了β2-微球蛋白与葡萄球菌A蛋白的反应，已知葡萄球菌A蛋白可与IgG的Fc区域发生反应。125I-β2-微球蛋白未与A蛋白结合。这可能是由于β2-微球蛋白与IgG的Fc区域之间氨基酸序列存在差异。
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