Loyola A M, de Araújo V C, de Sousa S O, de Araújo N S
Department of Oral Pathology, University of São Paulo, Brazil.
Eur J Cancer B Oral Oncol. 1995 May;31B(3):197-201. doi: 10.1016/0964-1955(95)00001-x.
One hundred and sixty-four cases of intraoral salivary gland tumours retrieved from the files of the Surgical Oral Pathology laboratory of the University of São Paulo (Brazil), between 1970 and 1993, were studied. Of these, 164 tumours, 62% were classified as benign and 38% malignant. The palate was the main site of occurrence of the tumours followed by the buccal mucosa and upper lip. There was a slight predominance for female patients, with a female to male ratio of 1.3:1. The mean age for benign tumours was 39.9 years (40.8 for females, and 39.7 for males). For malignant tumours the mean age was 43.5 years (42.6 for females and 44.7 for males). Pleomorphic adenoma was the most common of the benign tumours, whereas mucoepidermoid carcinoma and adenoid cystic carcinoma were the most common malignant tumours. In general, benign tumours presented as an asymptomatic nodule. On the other hand, pain, ulceration and radiographic changes were more frequently associated with malignant lesions.
对1970年至1993年间从巴西圣保罗大学口腔外科病理学实验室档案中检索出的164例口腔唾液腺肿瘤病例进行了研究。其中，164例肿瘤中，62%被分类为良性，38%为恶性。腭部是肿瘤的主要发生部位，其次是颊黏膜和上唇。女性患者略占优势，男女比例为1.3:1。良性肿瘤的平均年龄为39.9岁（女性为40.8岁，男性为39.7岁）。恶性肿瘤的平均年龄为43.5岁（女性为42.6岁，男性为44.7岁）。多形性腺瘤是最常见的良性肿瘤，而黏液表皮样癌和腺样囊性癌是最常见的恶性肿瘤。一般来说，良性肿瘤表现为无症状结节。另一方面，疼痛、溃疡和影像学改变更常与恶性病变相关。
