Bala R M, Wright C, Bardai A, Smith G R
J Clin Endocrinol Metab. 1978 Apr;46(4):649-52. doi: 10.1210/jcem-46-4-649.
Somatomedin bioactivity (SMA) in maternal serum, as measured by hypophysectomized rat cartilage assays, was low during early and late pregnancy but was similar to normal nonpregnant control levels near 28 weeks and at term pregnancy. At term, the mean level of SMA in cord serum was significantly less than in maternal serum, and greater than in amniotic fluid. The mean level of SMA in amniotic fluid was higher at term than in early pregnancy. No significant correlation was noted between SMA levels in amniotic fluid, maternal serum or cord serum, or between the SMA levels in these samples and the usual amniotic fluid parameters used as indices of fetal maturity.
通过垂体切除大鼠软骨试验测定，孕妇血清中的生长调节素生物活性（SMA）在妊娠早期和晚期较低，但在妊娠28周左右和足月时与正常非妊娠对照水平相似。足月时，脐血血清中SMA的平均水平显著低于母血血清，高于羊水。足月时羊水SMA的平均水平高于妊娠早期。羊水、母血血清或脐血血清中的SMA水平之间，以及这些样本中的SMA水平与用作胎儿成熟指标的常见羊水参数之间均未发现显著相关性。
