[Changes in the adrenergic innervation of the large intestine in the postnatal ontogeny of the white rat].

Age-related changes of adrenergic structures in intramural (myenteric and submucosal) plexuses of the albino rats large intestine were studied in different stages of postnatal ontogenesis (5 days, 1,5,13 and 24-26 months). It was established that adrenergic link of innervation develops most rapidly during the first month of postnatal life. This results in decrease of adrenergic nerve fibres number and catecholamine content in them with the simultaneous hypertrophy of part of the structures. Speed of the destructive processes development in the intestinal nerve plexuses grows with age, which leads to greater reduction of the adrenergic structures number.