Khussar Iu P, Milenin O V, Tiunder E O, Sillakivi T K, Pille A M
Department of Histology and Faculty Surgery, University of Tartu.
Morfologiia. 1995;108(1):71-5.
Histomorphological changes of revascularized autotransplant were studied in 34 dogs in different conditions of the operation. It was established that revascularization is necessary for transplantation. Organ disintegrates without vascular peduncle. Prolonged operative ischemia (up to 3 hrs) of the transplant causes its essential alternative and destructive changes up to the complete disintegration of part of the villi. Autotransplant of the small intestine preserves tissue and cell composition on the neck for a long period (more than a year) and may be used in replacing operations on the esophagus. However, complete organotypic and tissue restoration of the structure does not occur. Villi disappear, crypt epithelium forms structures resembling terminal regions of cardial glands, simple intestinal epithelium is replaced with the stratified one.
在34只处于不同手术条件的犬中研究了血管化自体移植的组织形态学变化。已确定血管化对于移植是必要的。没有血管蒂,器官就会解体。移植器官长时间的手术缺血(长达3小时)会导致其发生实质性的替代性和破坏性变化,直至部分绒毛完全解体。小肠自体移植可长期(超过一年)保持颈部的组织和细胞组成,可用于食管的替代手术。然而,结构并未完全恢复到器官型和组织型。绒毛消失,隐窝上皮形成类似贲门腺终末区域的结构,单层肠上皮被复层肠上皮取代。