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暴露于氮氧化物和氯混合物的大鼠外周血淋巴细胞中β-葡萄糖醛酸酶活性的变化

Changes of beta-glucuronidase activity in peripheral blood lymphocytes in rats exposed to a mixture of nitrogen oxides and chlorine.

作者信息

Starek A, Moszczyński P

出版信息

Pol J Pharmacol Pharm. 1978 Nov-Dec;30(6):819-24.

PMID:755246
Abstract

The activity of beta-glucuronidase (BG) was tested cytochemically in the lymphocytes of peripheral blood of rats exposed to a mixture of nitrogen oxides (1.22 mg/m3) and chlorine (1.02 mg/m3) for 12 weeks. The number of lymphocytes was reduced, the activity of BG was depressed and the enzyme was shifted from the lysosomes to the cytoplasm of these cells. A relation between the changes in the lymphocytes at the subcellular level and the immunological responses of the organism are discussed.

摘要

对暴露于氮氧化物（1.22毫克/立方米）和氯（1.02毫克/立方米）混合物中12周的大鼠外周血淋巴细胞进行了β-葡萄糖醛酸酶（BG）活性的细胞化学检测。淋巴细胞数量减少，BG活性降低，且该酶从这些细胞的溶酶体转移至细胞质。讨论了亚细胞水平上淋巴细胞的变化与机体免疫反应之间的关系。

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1
Changes of beta-glucuronidase activity in peripheral blood lymphocytes in rats exposed to a mixture of nitrogen oxides and chlorine.暴露于氮氧化物和氯混合物的大鼠外周血淋巴细胞中β-葡萄糖醛酸酶活性的变化
Pol J Pharmacol Pharm. 1978 Nov-Dec;30(6):819-24.
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