Moszczyński P, Moszczyński P, Sułowicz W
Folia Haematol Int Mag Klin Morphol Blutforsch. 1986;113(4):460-5.
The activity of acid phosphatase, beta-glucuronidase and N-acetyl-beta-glucosaminidase was assessed using semiquantitative cytochemical methods in peripheral blood lymphocytes of 45 untreated patients with gastric cancer and 80 healthy subjects. In cancer patients the study demonstrated a statistically significant decrease in the number of lymphocytes with granular reaction for acid phosphatase and N-acetyl-beta-glucosaminidase, as well as an increase in the number of lymphocytes showing a granular-diffuse reaction for the above enzymes and a diffuse reaction for all the studied lysosomal enzymes. Possible mechanisms of the observed changes are discussed.
采用半定量细胞化学方法，对45例未经治疗的胃癌患者及80名健康受试者外周血淋巴细胞中的酸性磷酸酶、β-葡萄糖醛酸酶和N-乙酰-β-氨基葡萄糖苷酶的活性进行了评估。研究表明，癌症患者中酸性磷酸酶和N-乙酰-β-氨基葡萄糖苷酶呈颗粒反应的淋巴细胞数量有统计学意义的减少，而上述酶呈颗粒-弥散反应以及所有研究的溶酶体酶呈弥散反应的淋巴细胞数量增加。文中讨论了所观察到变化的可能机制。
