高压氧治疗下颌骨放射性骨坏死：29例患者的经验
Hyperbaric oxygen treatment of osteoradionecrosis of the mandible. Experience in 29 patients.
作者信息
van Merkesteyn J P, Bakker D J, Borgmeijer-Hoelen A M
机构信息
Department of Oral and Maxillofacial Surgery, Academic Hospital Leiden, The Netherlands.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Jul;80(1):12-6. doi: 10.1016/s1079-2104(95)80009-3.
In recent years hyperbaric oxygen has gained an important role in the treatment of osteoradionecrosis of the mandible. In the treatment of 29 patients with osteoradionecrosis of the mandible, a combination of surgical debridement, antibiotics, and hyperbaric oxygen was used in 27 cases. In 20 of the 29 patients the osteoradionecrosis was considered to be resolved after treatment. In 31% of the patients, the continuity of the mandible was lost. It was concluded that combined treatment of surgical debridement, antibiotics, and hyperbaric oxygen gives acceptable results and may, when used in an early phase of the disease, limit the number of patients who lose continuity of the mandible.
近年来，高压氧在治疗下颌骨放射性骨坏死中发挥了重要作用。在治疗29例下颌骨放射性骨坏死患者时，27例采用了手术清创、抗生素和高压氧联合治疗。29例患者中有20例经治疗后放射性骨坏死被认为已得到解决。31%的患者下颌骨连续性丧失。得出的结论是，手术清创、抗生素和高压氧联合治疗取得了可接受的效果，并且在疾病早期使用时，可能会减少下颌骨连续性丧失的患者数量。
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