Kiss J, Schnitzer J
Acta Chir Acad Sci Hung. 1978;19(3):235-43.
After a review of the literature on antibiotic prophylaxis in thoracic surgery the authors present their own procedure, and point out the lack of difference between the therapeutic results and the incidence of complications in the groups treated with various antibiotics, and the control groups. Thus, routine prophylaxis is out-of-date, superfluous and even harmful in thoracic surgery. They are against preventive application in every case, but do not claim that antibiotics should never be applied. Pulmonary operations might be considered potentially infected; this, however, is not the same as an indication for prophylaxis. In thoracic surgery, preventive treatment is determined by individual indications and should always be of the aimed type. Antibiotics are dear, but their high price must not prevent their use, though the financial aspects of superfluously performed antibiotic prevention are not negligible.
在回顾了有关胸外科抗生素预防的文献后,作者介绍了他们自己的方法,并指出在接受各种抗生素治疗的组与对照组之间,治疗结果和并发症发生率并无差异。因此,常规预防在胸外科已过时、多余甚至有害。他们反对在每种情况下都进行预防性应用,但并不主张永远不使用抗生素。肺部手术可能被认为有潜在感染;然而,这与预防指征并不相同。在胸外科,预防性治疗由个体指征决定,且应始终是有针对性的。抗生素价格昂贵,但其高昂价格不应妨碍其使用,尽管不必要的抗生素预防所涉及的财务问题也不可忽视。