Lipkind M, Alexander D, Shihmanter E, Weisman Y, Collins M
Poultry Department, Kimron Veterinary Institute, Beit Dagan, Israel.
Comp Immunol Microbiol Infect Dis. 1995 Jun;18(3):189-207. doi: 10.1016/0147-9571(95)00003-q.
Thirty-three viruses of PMV-2 serotype isolated in Israel from domestic and wild birds during epizooty of a respiratory disease in 1979-1981 were studied comprehensively in comparison with a set of reference PMV-2 viruses using cross reaction hemagglutination inhibition tests, elution-hemagglutination pattern and pattern of migration of viral proteins in polyacrylamide gel electrophoresis. The results demonstrated considerable heterogeneity amongst the local isolates by the above three criteria which were not correlated with each other. There was no significant correlation between the differences found and chronology of isolation of the viruses. The results indicated that there may have been simultaneous co-circulation of different PMV-2 strains in the local avian reservoir at the beginning of the epizootic rather than temporal accumulation of variants as a result of antigenic drift of an "ancestor" virus which caused the initial infection.
1979 - 1981年以色列家禽和野鸟发生呼吸道疾病流行期间，从国内和野生鸟类中分离出33株PMV - 2血清型病毒，并与一组参考PMV - 2病毒进行比较，通过交叉反应血凝抑制试验、洗脱 - 血凝模式以及病毒蛋白在聚丙烯酰胺凝胶电泳中的迁移模式进行了全面研究。结果表明，根据上述三个标准，本地分离株之间存在相当大的异质性，且这三个标准之间互不相关。所发现的差异与病毒分离的时间顺序之间没有显著相关性。结果表明，在疫病流行初期，本地禽群中可能同时存在不同的PMV - 2毒株共同传播，而不是由于引起初始感染的“祖先”病毒的抗原漂移导致变体随时间积累。
