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对塑料和胶水系列进行变应原贴片试验反应的患者分析。

Analysis of patients with allergic patch test reactions to a plastics and glues series.

作者信息

Tarvainen K

机构信息

Department of Dermatology, University Central Hospital, Helsinki, Finland.

出版信息

Contact Dermatitis. 1995 Jun;32(6):346-51. doi: 10.1111/j.1600-0536.1995.tb00623.x.

DOI:10.1111/j.1600-0536.1995.tb00623.x
PMID:7554881
Abstract

839 patients were patch tested with a series of 31 plastics and glues allergens at a dermatologic clinic over a period of 7 years. 52 (6%) had a positive patch test reaction to 1 or more such allergens. Clinic charts of 47 patients (out of 52) were available for the study. All but 3 patients had dermatitis on their hands: 17 had only hand dermatitis. 25 (53%) patients' test results were of present or past relevance to their skin diseases. 11 patients (68%) with occupational allergic contact dermatitis (ACD) and 14 (45%) with non-occupational dermatitis had relevant reactions. p-tertiary-butylphenol-formaldehyde resin was the most common allergen (9 cases). 7 patients reacted to diaminodiphenylmethane. 5 patients, who had colophony allergy, reacted to abietic acid and 4 to abitol. There was no reaction to 14 test substances. Special series, such as this plastics and glues series, reveal the cause of ACD less frequently than standard series. However, there is no other way to confirm allergy to these usually industrial allergens, which can also sensitize through non-occupational exposure during hobby working or through unpolymerized monomer left in the finished plastic product.

摘要

在7年的时间里,839名患者在一家皮肤科诊所接受了一系列31种塑料和胶水过敏原的斑贴试验。52名(6%)患者对1种或更多此类过敏原的斑贴试验反应呈阳性。本研究获取了52名患者中47名患者的临床病历。除3名患者外,所有患者手部均有皮炎:17名患者仅有手部皮炎。25名(53%)患者的检测结果与他们目前或既往的皮肤病有关。11名(68%)职业性过敏性接触性皮炎(ACD)患者和14名(45%)非职业性皮炎患者有相关反应。对叔丁基苯酚甲醛树脂是最常见的过敏原(9例)。7名患者对二氨基二苯甲烷有反应。5名患有松香过敏的患者对枞酸有反应,4名对枞醇有反应。14种测试物质无反应。像这种塑料和胶水系列的特殊系列,相较于标准系列,较少揭示ACD的病因。然而,没有其他方法可以确认对这些通常为工业用过敏原的过敏情况,这些过敏原也可通过业余工作时的非职业性接触或成品塑料中残留的未聚合单体致敏。

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