Takano Y
Department of Oral Anatomy II, Niigata University School of Dentistry, Japan.
Connect Tissue Res. 1995;33(1-3):127-37. doi: 10.3109/03008209509016992.
Amelogenesis is a dynamic and unique process of cell-matrix interactions in that matrix synthesis, degradation and resorption all proceed simultaneously, coupled with mineral depositions in a compartment between ameloblasts and dentin or dental papilla. Accumulation of data suggest the role of ameloblasts in tooth morphogenesis and matrix formation, but no fully acceptable explanation has been given concerning the role of ameloblasts in calcium transport. In this article, old and new points of issue raised regarding the role of ameloblasts in calcium acquisition are reviewed and possible mechanisms whereby the ameloblasts prevent the rise of cytosolic calcium while actively or less actively transporting calcium are elaborated upon based on recent findings.
釉质形成是一个细胞与基质相互作用的动态且独特的过程，在此过程中，基质的合成、降解和重吸收同时进行，同时在成釉细胞与牙本质或牙髓之间的腔隙中伴有矿物质沉积。大量数据表明成釉细胞在牙齿形态发生和基质形成中发挥作用，但关于成釉细胞在钙转运中的作用，尚未给出完全可接受的解释。在本文中，我们回顾了关于成釉细胞在钙摄取中作用的新老问题，并根据最近的研究结果阐述了成釉细胞在主动或非主动转运钙的同时防止胞质钙升高的可能机制。
