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一种用于竞争风险分组生存数据广义卡方分析的计算机程序(CRISCAT)。

A computer program for the generalized chi-square analysis of competing risks grouped survival data (CRISCAT).

作者信息

Stanish W M, Chi G Y, Johnson W D, Koch G G, Landis J R, Liu-Chi S

出版信息

Comput Programs Biomed. 1978 Sep;8(3-4):208-23. doi: 10.1016/0010-468x(78)90028-4.

Abstract

CRISCAT is a computer program for the analysis of grouped survival data with competing risks via weighted least squares methods. Competing risks adjustments are obtained from general matrix operations using many of the strategies employed in a previously developed program (GENCAT) for multivariate categorical data. CRISCAT computes survival rates at several time points for multiple causes of failure, where each rate is adjusted for other causes in the sense that failure due to thes other causes has been eliminated as a risk. The program can generate functions of the adjusted survival rates, to which asymptotic regression models may be fit. CRISCAT yields test statistics for hypotheses involving either these functions or estimated model parameters. Thus, this computational algorithm links competing risks theory to linear models methods for contingency table analysis and provides a unified approach to estimation and hypothesis testing of functions involving competing risks adjusted rates.

摘要

CRISCAT是一个通过加权最小二乘法分析具有竞争风险的分组生存数据的计算机程序。竞争风险调整是通过一般矩阵运算获得的,使用了先前开发的用于多变量分类数据的程序(GENCAT)中采用的许多策略。CRISCAT计算多个失败原因在几个时间点的生存率,其中每个率都针对其他原因进行了调整,即由于其他原因导致的失败已被消除为一种风险。该程序可以生成调整后生存率的函数,可以拟合渐近回归模型。CRISCAT产生涉及这些函数或估计模型参数的假设的检验统计量。因此,这种计算算法将竞争风险理论与用于列联表分析的线性模型方法联系起来,并为涉及竞争风险调整率的函数的估计和假设检验提供了一种统一的方法。

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